Academic Research Journal•2026•DOI: 10.26599/NR.2026.94908819
Periodontitis, a chronic inflammatory disease caused by bacterial biofilms, leads to alveolar bone resorption and tooth loss. Current treatments fail to eradicate biofilms and reverse inflammation-induced bone loss. Here, we developed an injectable hydrogel (GQM) composed of oxidized gellan gum, quaternized chitosan, and magnesium–tannic acid-modified MXene nanosheets (MTA-Mg). GQM is injectable into periodontal pockets and delivers MTA-Mg, which disrupts biofilms via photothermal effect under near-infrared (NIR) laser irradiation and kills bacteria through electrostatic interactions from quaternized chitosan. MTA-Mg also acts as an interfacial electron transfer agent to activate oxidative phosphorylation, while releasing magnesium and tannic acid to improve mitochondrial function, thereby reprogramming immune cell metabolism toward the M2 macrophage phenotype. In a rat periodontitis model, GQM hydrogel effectively eradicated biofilms, alleviated inflammation, and reversed alveolar bone resorption. This synergistic 'biofilm disruption–immune metabolic reprogramming' strategy offers a novel approach for treating inflammatory bone resorption in periodontitis.
Int. Journal of Mining Science and Technology (采矿与安全工程)•2026•DOI: 10.1016/j.ijmst.2026.01.001
In igneous-intruded coal seams, coal undergoes significant metamorphism, which critically alters its pore structure and oxygen consumption dynamics, thereby elevating its spontaneous combustion tendency. This study investigates the specific surface area, pore volume, structure complexity/connectivity, heterogeneity/local features of pore size distribution, and oxygen consumption dynamics of igneous metamorphic coal through N2/CO2 isothermal adsorption tests and low-temperature oxidation experiments, and elucidates the influence mechanisms of pore structure evolution on oxygen consumption dynamics during low-temperature oxidation. With increasing metamorphic degree, igneous metamorphic coal exhibits a more pronounced reduction in specific surface area during oxidation, while the increase in structure complexity due to coal-oxygen reactions is suppressed. Thermally metamorphic coal demonstrates accelerated oxygen consumption, with oxidation amplifying the difference in reaction rates compared to raw coal. Key mechanisms include oxidation-induced reduction in mesopore complexity and micropore volume, decreased dominance of small-pore-volume apertures, and increased heterogeneity, collectively leading to a lower half-oxygen-consuming temperature and steeper oxygen consumption curves. Simultaneously, increased pore volume/complexity and reduced uniformity/connectivity act synergistically to enhance oxygen consumption capacity, highlighting the coupling between pore structure evolution and oxidation behavior in igneous metamorphic coal. This study provides theoretical insights into the pore-oxygen coupling mechanisms governing coal spontaneous combustion in igneous intrusion areas.
Int. Journal of Mining Science and Technology (采矿与安全工程)•2025•DOI: 10.1016/j.ijmst.2025.08.010
The spatiotemporal characterization of plume sedimentation and microorganisms is critical for developing plume ecological monitoring models. To address the limitations of traditional methods in obtaining high-quality sediment, a novel sampling system with 6000 m operational capability and three-month endurance was developed. It is equipped with three sediment samplers and a set of formaldehyde preservation solution injection devices. The system is controlled by a low-power, timing-triggered controller. To investigate low-disturbance rheological mechanisms, gap-controlled rheological tests were conducted to optimize the structural design of the sampling and sealing assembly. Stress-controlled shear rheological tests were employed to investigate the mechanisms governing yield stress in sediments under varying temperature conditions and boundary roughness. Additionally, the coupled Eulerian-Lagrangian (CEL) method and sediment rheological constitutive models were employed to simulate tube-soil interaction dynamics and sediment disturbance. The radial heterogeneity of sediment disturbance and friction variation of the sampling tube were revealed. The tube was completely "plugged" at a penetration depth of 261 mm, providing critical data support for penetration depth parameters. The deep-sea pressure test and South China Sea field trials demonstrated the system's capability to collect and preserve quantitative time-series sediment samples with high fidelity.
Int. Journal of Minerals, Metallurgy and Materials (矿物冶金与材料学报)•2025•DOI: 10.1007/s12613-024-3050-1
The development of stretchable conductors with high deformation, conductivity, and thermal conductivity using liquid metal (LM) has sparked widespread interest in the fields of flexible electronics, electromagnetic interference (EMI), and multifunctional materials. However, fabricating desirable shielding materials by directly coating LMs on soft polymer substrates remains a challenge because of the huge surface tension and weak wettability of LMs. In this study, Ga-based composite paste is prepared from a mixture of Ga and diamond nonmetallic particles through ultrasonic fragmentation. At various temperatures, the resulting LM composite putty (LMP) exhibits soft and hard properties and can thus be molded into specific shapes according to application needs. In addition, the composite can be easily coated onto polymer substrates, such as thermoplastic polyurethane (TPU) elastomer. The fabricated LMP–TPU exhibits an impressive shape deformation capacity of 1100%, demonstrating exceptional tensile properties and achieving electromagnetic interference–shielding effectiveness of up to 52 dB. Furthermore, it retains an ultrahigh conductivity of 20000 S/m, even under a strain of 600%. This feature further makes it a highly competitive multifunctional material.