Two-Dimensional TiO2 Ultraviolet Filters for Sunscreens

• Two-dimensional (2D) TiO2 was developed with >99% visible light transmittance for non-whitening UV protection, outperforming conventional 0D TiO2 in aesthetics while matching UV-blocking efficacy. • 2D TiO2 achieves ultralow skin penetration and 90% reduced reactive oxygen species generation versus 0D TiO2, eliminating photocatalytic toxicity and DNA damage risks. • 2D TiO2 enabled tunable UVA/UVB coverage via metal doping without compromising visible light transmittance, ensuring Scientific Committee on Consumer Safety compliance and biocompatibility. • We integrated high UV protection, natural appearance, and photoinertness into a single material, redefining aesthetic-safe sunscreen design through 2D structural innovation.