• State-of-the-art methods for introducing local strain into 2D TMDCs, including AFM tips, pre-strained elastomer substrates, and templated structures, are systematically reviewed.
• Local strain engineering enables precise modulation of optical properties and excitonic behaviors, such as exciton funnelling and anti-funnelling, in 2D TMDCs.
• Strained 2D TMDCs serve as deterministic quantum emitters with tunable emission energies, offering a promising platform for single-photon sources in quantum technologies.
• The review highlights the potential of 2D TMDC-based quantum emitters for integration into optical cavities and waveguides, enhancing coherence and brightness for practical quantum applications.