• A physical computational model was established to relate the electron-multiplication layer to noise characteristics in uniformly doped P-type substrate EBCMOS chips.
• Optimization of passivation layer (Al2O3, 15 nm) and substrate temperature (260 K) significantly improves noise performance.
• Decreasing P-substrate doping concentration and thickness, while increasing incident electron energy, enhances SNR.
• Dark current noise, primarily governed by interfacial defects, has a substantial impact on overall device noise characteristics.
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