• Laser cladding of Ti50Nb15V15Zr5Cr5Al10 high-entropy alloy on Ti6Al4V produces a single body-centered cubic phase coating with significantly enhanced hardness compared to the substrate.
• The HEA coating fabricated at 2200 W exhibits the best wear and corrosion resistance, with wear volumes only 24.7%–45.5% of the substrate and corrosion rate reduced by an order of magnitude.
• Adhesive wear dominates the friction mechanism, with high-temperature oxide formation contributing to the tribological behavior.
• The presence of Cr and Al promotes the formation of a dense passive film, which is key to the improved corrosion resistance of the coatings.