• Bimetallic single-atom catalysts (bimSACs) leverage synergistic interactions between two metal centers, enhancing catalytic performance for water splitting.
• The review highlights advanced characterization techniques and computational methods for understanding bimSACs' electronic and coordination properties.
• BimSACs show promise in both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER), addressing limitations of single-atom catalysts.
• The work underscores the potential of bimSACs to enable sustainable, cost-effective green hydrogen production, contributing to global energy transition.