Synthesis Strategies and Multi-field Applications of Nanoscale High-Entropy Alloys

• Nanoscale high-entropy alloys (HEAs) exhibit superior catalytic, biomedical, and energy storage properties due to increased surface-active sites and tunable electronic structures. • Bottom-up synthesis strategies (e.g., hydrothermal, one-pot) enable precise control over size, composition, and atomic ordering, overcoming limitations of conventional top-down methods. • Multi-field applications of nanoscale HEAs span catalysis, biomedicine, and energy storage, with recent advances highlighting their potential in efficient and sustainable technologies. • Future development trends focus on nanosizing and multidimensionalization to further enhance performance and expand application horizons.