• A novel b-cyclodextrin-immobilized sodium alginate aerogel (b-CD/NaAlg) was synthesized via epichlorohydrin cross-linking, exhibiting a three-dimensional porous network.
• Under optimal conditions, the adsorbent achieved 70% tetracycline removal, with adsorption fitting the Freundlich isotherm and pseudo-second-order kinetics.
• Integration with ultrafiltration enhanced tetracycline removal to 78.9% within 2 hours, demonstrating practical applicability for reclaimed water treatment.
• The adsorbent maintained 55.3% removal efficiency after five cycles, highlighting its reusability and sustainability.
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