• A finite element model of solidification and heat transfer was established for the secondary cooling process of S30432 continuous casting billet, enabling systematic study of process parameters.
• Orthogonal experiments revealed the coupling effects of casting speed, superheat, and specific water flow on solidification structure, leading to optimized process parameters.
• Production verification showed that coarse niobium compound enrichment causes inner wall cracks during hot piercing, and optimized parameters mitigate Nb segregation and improve grain refinement.
• The synergistic decrease of superheat and increase of specific water flow promotes equiaxed crystal zone expansion, improving billet quality and hot workability.
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