Highly Permeable and Liquid-Repellent Textiles with Micro-Nano-Networks for Medical and Health Protection

• A novel non-solvent induced phase separation method using CaCl2 and fluorinated polyurethane enables scalable fabrication of highly permeable protective textiles (HPPT) with micro/nano-network structures. • The optimized HPPT achieves a balance between protection and comfort: high hydrostatic pressure (12.86 kPa) and small pore size (1.03 μm) ensure liquid repellency, while high porosity (69%) and interconnected pores provide excellent air (14.24 mm/s) and moisture (7.92 kg/m²/d) permeability. • Molecular dynamics simulations and dynamic phase transition observations reveal the diffusion–dissolution–phase separation mechanism, offering theoretical guidance for pore structure regulation in protective textiles. • The HPPT outperforms commercial protective materials in comfort, presenting a promising solution to enhance healthcare worker performance and well-being during prolonged wear.