• Integrative Co-Design Framework: Synthesizes advances in sensing, models, accuracy/reliability assessment, and hardware into a sensor–model–deployment–assessment framework, balancing precision and efficiency for cuffless BP monitoring.
• Pathways to Clinical Translation: Critically assesses barriers to real-world deployment, offering actionable strategies to bridge the translational gap for scalable implementation in low-resource regions.
• Interdisciplinary Synthesis: Integrates materials science, digital health, and embedded AI to provide evidence-based recommendations for equitable diagnostic solutions.
• Global Health Equity: Emphasizes potential of AI-enhanced wearable BP monitoring to support proactive hypertension control and promote cardiovascular health equity worldwide.